COST Action CA18139

Genomics of MusculoSkeletal traits Translational Network

Join the Action

The Action is an open, interdisciplinary and growing network welcoming academics, practitioners and relevant stakeholders to contribute to the activities of the GEMSTONE.

Description

The musculoskeletal system is a key element for healthy aging, being mobility a fundamental component of quality of life, health, and independence of aging individuals.
The unprecedented amount of discoveries arising from genome-wide association studies (GWAS) have set a new era full of translational potential in the field of musculoskeletal biology. Coupled to the growing understanding of monogenetic disorders, the GWAS discoveries have set a roadmap characterizing the biological pathways underlying the musculoskeletal metabolism. The musculoskeletal field is now confronted with new biology arising in the form of novel factors clustering in known molecular pathways but also with novel factors whose role and function remains to be elucidated.

Several opportunities to increase the amount of discoveries like the imminence of whole-genome sequencing efforts, the advent of a new generation of “very-low cost” GWAS arrays and the availability of very large mega GWAS studies like the UKBIOBANK are now in place. The challenge is now about bringing the knowledge arising from high-throughput analysis of increasingly available BIG DATA to a larger set of researchers, who can both contribute to 1) generating additional genetic discoveries and 2) setting the ground for their functional characterization in order to translate these genetic discoveries into meaningful clinical applications. To do this, GEMSTONE will be the mechanism to reach out to a wider range of researchers active in musculoskeletal biology, in order to fuel the production of discoveries and their biological relevance, which will allow their translation to treatments and new molecular definitions.

Latest News

Virtual Networking Tools (VNT)are tools that COST has made available to facilitate virtual networking in order to: support individual mobility strengthen existing networks fostering collaboration between COST Action participants There...
If you are interested in attending the meeting, please send an email to info@gemstone.org All GEMSTONE members will receive an invitation through eCOST. Download program here
Barbara Voraberger is a Ph.D. student in the research group of Prof. Dr. Wolfgang Högler at the Johannes Kepler University in Linz, Austria. The laboratory focus is on understanding the...
A position as postdoc is vacant at the laboratory of associate professor Kent Søe, Clinical Cell Biology, Pathology Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark....
The 2nd Short Term Scientific Missions (STSMs) call for the GEMSTONE Action is now open. STSMs are exchange visits aimed at: >Supporting individual mobility >Strengthening existing networks >Fostering collaboration between COST...
Above all, let us wish you this message finds you and your beloved in good health during this difficult COVID-19 period. If not, we wish you character and strength to...