Goal of Workshop:
Training on translational techniques following the identification of underlying genetic defects in monogenic rare bone disorders, including the use and benefits of animal models in translational research and drug discovery. Different rare bone disorders will be discussed, such as Osteogenesis Imperfecta, Fibrodysplasia Ossificans Progressiva, familial early-onset Osteoporosis and high bone mass disorders, and examples of novel treatment options will be showcased.
Transfer of knowledge and skills to sectors and partners of COST Inclusiveness Target Countries. Transfer of knowledge and skills between the scientific community for prioritisation of potentially causal genes, functional assessment of these genes, and how the genetic findings can lead to identification of drug targets. Exchange of skills and knowledge regarding new methodology with young researchers.
Goal of Networking Event:
The one-day training School aims to target early career investigators, PhD students, clinical and basic scientists.
The workshop will feature different translational tools that can be used to investigate novel genetic and genomic findings, use of animals as translational model systems in different monogenic bone disorders, clinical spectrum of monogenic bone disorders, and examples of how translational research has aided in the discovery of drug targets for monogenic bone disorders.
The workshop will take place on the 23rd of September. It will be part of the annual GEMSTONE meeting, which will take place on the 21st of September, followed by a workshop organised by WG2 on the 22nd of September.