Guidelines and detailed methodology for standardized evaluation of bone remodeling (bone formation and resorption) in the femur and/or lumbar vertebra. This hands-on is especially recommended for those who attended the introductory workshop in 2021. All “YRI” (Young Researcher and Innovator) of the network will be invited. If the number of applying trainees exceeds 15, a selection based on CV will be made. The selected trainees will be prioritized as follows: 1. Affiliation in ITC 2.Career stage (the earlier career stage will be prioritized) 3. WG membership 4. Sex balance